Press Releases

Neutrophils isolated from the bone marrow of mouse models and patients with early stage tumors exhibit increased spontaneous migration to tissues and promote tumor cell seeding. 

DNA vaccines are safe and offer an alternative to traditional vaccines for immunization of vulnerable at-risk populations.

BCL2 inhibitors may provide a novel therapeutic strategy to prevent or overcome acquired resistance to EZH2 inhibitors in ARID1A-mutant cancers.

This novel approach opens new avenues of research and may expand clinical approaches for cancer immunotherapy.

PHILADELPHIA — (Oct. 2, 2018) — Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute. These changes are caused by loss of the HAPLN1 protein, which is part of the extracellular matrix, during aging. The studies were published back-to-back in Cancer Discovery.