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Gram Negative Conference Banner - 2019

Symposium on Gram Negative Bacteria Resistance

Symposium
Wednesday, Jul. 31, 2019 8:30 a.m. to 6:00 p.m.

The conference focuses on pathophysiology and prevention of gram-negative bacteria. The goal is to bring together leading investigators in the field for in-depth discussions on the current global state of infections that drive antimicrobial resistance (AMR). Perspectives to be covered include strategies to exploit novel bacterial vulnerabilities, updates on cutting-edge approaches towards gram-negative infections and the next steps in combating AMR.

The Wistar Institute
3601 Spruce Street
Philadelphia, PA 19104

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Robert A. Bonomo, M.D.

Robert A. Bonomo, M.D.
Case Western Reserve University School of Medicine
Louis Stokes Cleveland Department of Veteran Affairs Medical Center

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Farokh Dotiwala, MBBS, Ph.D.

Farokh Dotiwala, MBBS, Ph.D.
The Wistar Institute

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Thomas J. Hannan, D.V.M., Ph.D.

Thomas J. Hannan, D.V.M., Ph.D.
Washington University School of Medicine
Fimbrion Therapeutics Inc.

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Jonathan Koff, M.D.

Jonathan Koff, M.D.
Yale School of Medicine

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Rahul M. Kohli, M.D., Ph.D.

Rahul M. Kohli, M.D., Ph.D.
University of Pennsylvania, Perelman School of Medicine

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Myron Levine, M.D., DPTH

Myron Levine, M.D., DPTH
University of Maryland School of Medicine

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Paul A. Offit, M.D.

Paul A. Offit, M.D.
Children’s Hospital of Philadelphia

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Ami Patel, Ph.D.

Ami Patel, Ph.D.
The Wistar Institute

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Sanjay Ram, M.D.

Sanjay Ram, M.D.
University of Massachusetts Medical School

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Oren Rosenberg, M.D., Ph.D.

Oren Rosenberg, M.D., Ph.D.
University of California, San Francisco

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Raphael Simon, Ph.D.

Raphael Simon, Ph.D.
Pfizer

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Pranita D. Tamma, M.D.

Pranita D. Tamma, M.D.
Johns Hopkins Medicine

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David B. Weiner, Ph.D.

David B. Weiner, Ph.D.
The Wistar Institute

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Helen I. Zgurskaya, Ph.D.

Helen I. Zgurskaya, Ph.D.
University of Oklahoma

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Daniel V. Zurawski, Ph.D.

Daniel V. Zurawski, Ph.D.
Walter Reed Army Institute of Research

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8:30 - 8:45 AM  

Opening Remarks
David B. Weiner, Ph.D., The Wistar Institute
Emily Kramer-Golinkoff, Emily’s Entourage

8:45 - 9:15 AM  

"Important Gram-Negative Publications from the Past Year"
Pranita D. Tamma, M.D.
Johns Hopkins Medicine

9:15 - 9:45 AM  

“Beta-lactamase Inhibitors: A Renaissance”
Robert Bonomo, M.D.
Case Western Reserve University School of Medicine
Louis Stokes Cleveland Department of Veteran Affairs Medical Center

9:45 - 10:15 AM  

"New Strategies for Combating Urinary Tract Infections: Targeting the Mucosal Immune Response and Bacterial Virulence"
Thomas J. Hannan, D.V.M., Ph.D.
Washington University School of Medicine, St. Louis
Fimbrion Therapeutics, Inc.

10:15 - 10:40 AM  

Break

10:45 - 11:05 AM  

“Neisseria gonorrhoeae: Targeting Virulence Mechanisms to Develop Novel Immunotherapeutics and Vaccines"
Sanjay Ram, M.D.
University of Massachusetts Medical School

11:05 - 11:25 AM  

“Novel Therapeutic Approaches for Acinetobacter baumanii Infection"
Daniel Zurawski, Ph.D. 
Walter Reed Army Institute of Research

11:25 - 11:45 AM  

“Disarming the SOS Response to Combat the Evolution of Antibiotic Resistance"
Rahul M. Kohli, M.D., Ph.D.
University of Pennsylvania, Perelman School of Medicine

11:45 - 12:05 PM  

“Reimagining Bacteriophages to Treat Multi-drug Resistant Infections"
Jonathan Koff, M.D.
Yale School of Medicine 

12:05 - 1:00 PM  

Lunch

1:00 - 1:25 PM  

“New Genetic Tools for the Study of Gram-negative Pathogens"
Oren Rosenberg, M.D., Ph.D.
University of California, San Francisco

1:25 - 1:50 PM  

“IspH Inhibitors as Dual Acting Immune Antibiotics"
Farokh Dotiwala, MBBS, Ph.D.
The Wistar Institute 

1:50 - 2:15 PM  

“An Integrative Approach to Multidrug Efflux and Its Inhibition"
Helen I. Zgurskaya, Ph.D.
University of Oklahoma

2:15 - 2:45 PM  

Break

2:50 - 3:10 PM  

“Current and Future Vaccines Against Major Bacterial Enteropathogens (Salmonella, Shigella, Enterotoxigenic Escherichia coli and Vibrio cholerae O1)  that are Increasingly Resistant to Multiple Antibiotics: Lessons Learned."
Myron M. Levine, M.D., DTPH
University of Maryland School of Medicine 

3:10 - 3:30 PM  

"Pseudomonas Immunotherapy: Strategies Using In Vivo DNA Delivery of Monoclonal Antibodies to Control Multidrug-resistant Pseudomonas aeruginosa"
Ami Patel, Ph.D.
The Wistar Institute

3:30 - 3:50 PM  

“Carbohydrate Vaccine Approaches for Prevention of Gram-negative Bacterial Infections."
Raphael Simon, Ph.D.
Pfizer 

3:50 - 4:10 PM  

Break

4:10 - 5:00 PM  

Panel Discussion
Moderated by Paul A. Offit, M.D.
Children’s Hospital of Philadelphia

5:00 - 6:00 PM  

Reception