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The Wistar Institute

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Moving the Needle Forward: Wistar Research Leads to a Coronavirus Vaccine Entering Human Trials and Additional Wistar Coronavirus Research Projects Underway

While the world struggles with a growing number of people sickened with COVID-19 and health care workers engage in a tireless and heroic mission to save lives, biomedical researchers are on the front lines of a parallel and equally critical b…
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Reflections on the COVID-19 Crisis and How Wistar is Making a Difference

Dr. Dario Altieri, Wistar president and CEO, gets candid about our response as a country to the COVID-19 pandemic, and how the Institute is advancing scientific solutions to protect those at the frontlines. The streets of University City Philadelp…
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Wistar Translational Research in Response to the COVID-19 Pandemic

The Wistar Institute’s Vaccine & Immunotherapy Center (VIC) has assembled its expertise in infectious disease research, as its scientists are part of a team racing to provide a countermeasure for the ongoing coronavirus outbreak…
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Wistar Expands Its Training Program With Support From the PA Department of Labor & Industry

On March 12, the Pennsylvania Department of Labor & Industry (L&I) announced more than $6.5 million in PAsmart Registered Apprenticeship Grants. Wistar is one of the awarded institutions, receiving a $212,499 grant in support of the Expans…
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Coming of Age: The Creation of the HPV Vaccine 

Human papillomavirus (HPV) is the most commonly sexually transmitted virus in the world, infecting 75% of sexually active adults in their lifetime1. HPV infection has a dramatic impact on global health, with more than 500,000 cervical cancer …
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Coupling Computational Protein Engineering with Synthetic DNA Technology Enhances Nanovaccine Efficacy Allowing the Patient’s Own Body to Customize Production

PHILADELPHIA — (March 11, 2020) — Scientists at The Wistar Institute reported a sophisticated technology to simplify production of nanovaccines, a novel approach to vaccination that can robustly stimulate immunity in preclinical models. The study,…
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A New Generation of Cancer Researchers at Wistar

Expanding the faculty and enhancing its multidisciplinary nature are focal points in Wistar’s Cancer Center under the leadership of Dario Altieri, M.D., president and CEO, director of The Wistar Institute Cancer Center, and Robert and Penny Fox Di…
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Women & Science: Becoming a Leader and a Role Model 

At the latest installment of Wistar’s Women & Science Program, guest speaker Dr. Padmanee Sharma, a distinguished clinician and researcher who has focused her career on understanding how to boost the human immune system to treat cancer, shared…
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Vaccination Exploration: The Case of Measles, Mumps and Rubella 

Getting sick with these childhood diseases could mean much more than a fever and a rash. A brief history of vaccination Infectious diseases have existed alongside (and within) humans throughout history. Efforts to prevent contagion have been attem…
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New Molecular Mechanism Involved in Cellular Senescence That Modulates Inflammation and Response to Cancer Immunotherapy 

PHILADELPHIA — (Feb. 19, 2020) — Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence. This pathway may be modulated during senescence-induci…