The Wistar Institute
Women & Science: Developing Immunotherapies for Emerging Pathogens That Threaten Global Health
Wistar’s first Women & Science event of the COVID-19 era took place virtually and, appropriately, featured Dr. Ami Patel, a Wistar scientist that is playing a major role in the work being done at the Institute to develop solutions for the pand…
Wistar Appoints Ami Patel, Ph.D., as Caspar Wistar Fellow
PHILADELPHIA — (Sept. 14, 2020) — The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease research, and vaccine creation, announces the appointment of Ami Patel, Ph.D., as a Caspar Wistar Fellow …
Scientists Engineer DNA-based Nanotechnology to Stimulate Potent Antitumor Immune Responses in Preclinical Models
PHILADELPHIA — (Sept. 10, 2020) — Combining their expertise in protein engineering and synthetic DNA technology, scientists at The Wistar Institute successfully delivered nanoparticle antitumor vaccines that stimulated robust CD8 T cell immunity a…
The BEAT-HIV Martin Delaney Collaboratory Issues Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials
PHILADELPHIA — (Sept. 7, 2020) — Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled…
Scientists Use Knowledge From Traditional Medicine to Discover Drugs to Fight the Pandemic
Dr. Ian Tietjen came to Wistar in 2019 as a research assistant professor in the laboratory of Dr. Luis Montaner. He brings a fascinating approach to HIV and infectious disease research that explores the traditional medicine knowledge of …
Wistar Science Highlights: New Discoveries on HIV Latency and How Cancer Cells Talk With Their Neighboring Normal Cells
Antiretroviral therapy (ART) has dramatically increased the health and life expectancy of HIV-infected individuals, suppressing virus replication in the host immune cells and stopping disease progression; however, low yet persistent amounts o…
Breast Cancer Cells Use Message-carrying Vesicles to Send Oncogenic Stimuli to Neighboring Normal Cells
PHILADELPHIA — (Aug. 10, 2020) — According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells. These messages are packaged into particle…
New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy
PHILADELPHIA — (August 4, 2020) — Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART). These findings were published today in …
Workforce Development at Wistar: Life Science Students Gain Valuable Research Experience During the COVID-19 Pandemic
As our state economy faces a long slog back to recovery from the COVID-19 pandemic, Wistar is poised to assist with the development of the workforce that will help enable that recovery. The Institute’s education and training programs provide …
Spotlight on Wistar COVID-19 Researcher: Paul Lieberman, Ph.D.
Creating a new drug from scratch takes many years and billions of dollars. While discovery of new molecules against SARS-CoV-2 and other emerging viruses is imperative, the world also needs solutions for COVID-19 now. This is why there has been wi…