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The Wistar Institute

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Women & Science: Developing Immunotherapies for Emerging Pathogens That Threaten Global Health

Wistar’s first Women & Science event of the COVID-19 era took place virtually and, appropriately, featured Dr. Ami Patel, a Wistar scientist that is playing a major role in the work being done at the Institute to develop solutions for the pand…
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Wistar Appoints Ami Patel, Ph.D., as Caspar Wistar Fellow

PHILADELPHIA — (Sept. 14, 2020) — The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease research, and vaccine creation, announces the appointment of Ami Patel, Ph.D., as a Caspar Wistar Fellow …
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Scientists Engineer DNA-based Nanotechnology to Stimulate Potent Antitumor Immune Responses in Preclinical Models

PHILADELPHIA — (Sept. 10, 2020) — Combining their expertise in protein engineering and synthetic DNA technology, scientists at The Wistar Institute successfully delivered nanoparticle antitumor vaccines that stimulated robust CD8 T cell immunity a…
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The BEAT-HIV Martin Delaney Collaboratory Issues Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials

PHILADELPHIA — (Sept. 7, 2020) — Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled…
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Scientists Use Knowledge From Traditional Medicine to Discover Drugs to Fight the Pandemic

Dr. Ian Tietjen came to Wistar in 2019 as a research assistant professor in the laboratory of Dr. Luis Montaner. He brings a fascinating approach to HIV and infectious disease research that explores the traditional medicine knowledge of …
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Wistar Science Highlights: New Discoveries on HIV Latency and How Cancer Cells Talk With Their Neighboring Normal Cells

Antiretroviral therapy (ART) has dramatically increased the health and life expectancy of HIV-infected individuals, suppressing virus replication in the host immune cells and stopping disease progression; however, low yet persistent amounts o…
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Breast Cancer Cells Use Message-carrying Vesicles to Send Oncogenic Stimuli to Neighboring Normal Cells 

PHILADELPHIA — (Aug. 10, 2020) — According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells. These messages are packaged into particle…
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New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy

PHILADELPHIA — (August 4, 2020) — Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART). These findings were published today in …
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Workforce Development at Wistar: Life Science Students Gain Valuable Research Experience During the COVID-19 Pandemic

As our state economy faces a long slog back to recovery from the COVID-19 pandemic, Wistar is poised to assist with the development of the workforce that will help enable that recovery. The Institute’s education and training programs provide …
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Spotlight on Wistar COVID-19 Researcher: Paul Lieberman, Ph.D.

Creating a new drug from scratch takes many years and billions of dollars. While discovery of new molecules against SARS-CoV-2 and other emerging viruses is imperative, the world also needs solutions for COVID-19 now. This is why there has been wi…