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The Wistar Institute

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Wistar Researchers Develop New Humanized Mouse Model That Provides Insight Into Immunotherapy Resistance

PHILADELPHIA — (Jan. 12, 2021) — Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central ro…
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Wistar Scientists Target an Alternative Fuel Source of Cancer Cells as a Therapeutic Approach for Breast Cancer

PHILADELPHIA — (Jan. 7, 2021) — Scientists at The Wistar Institute characterized an inhibitor that targets acetate metabolism in cancer cells. Cancer cells use acetate metabolism to support tumor growth in conditions of low nutrient and oxygen avail…
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DARPA and JPEO-CBRND Award $37.6M to The Wistar Institute and Collaborators at INOVIO, AstraZeneca, Penn, & Indiana University to Develop Innovative COVID-19 Treatment

PHILADELPHIA — (Dec. 15, 2020) — A team of scientists from The Wistar Institute, INOVIO, AstraZeneca, the Perelman School of Medicine at the University of Pennsylvania, and Indiana University has received a $37.6 million award over two years from th…
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Dr. Chi Van Dang Ranks in the 2020 Highly Cited Researchers List

Dr. Dang, a world-renowned scientist, medical oncologist, National Academy of Medicine member, and professor in Wistar’s Molecular and Cellular Oncogenesis Program, was selected for the 2020 Highly Cited Researchers list compiled by Clarivate Analyt…
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Sarah Welsh and Joseph Zundell Share the 2020 Monica H. M. Shander Memorial Fellowship Award

Predoctoral trainees Sarah Welsh and Joseph Zundell are the recipients of the annual Monica H. M. Shander Memorial Fellowship Award for outstanding predoctoral research. This year, the Committee has voted unanimously to split the award between both…
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Wistar’s Graduate Student Pratik Bhojnagarwala Awarded the Abraham Schlussel Women’s Health Fellowship Award for Ovarian Cancer Research

Pratik Bhojnagarwala is a third-year graduate student in the Cancer Biology Program jointly administered by Wistar and the University of the Sciences. Currently, he’s carrying out thesis work in the Wistar lab of Dr. David Weiner, focusing on design…
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Wistar Virtual Champion Run for Research 2020

From the many corners of Philadelphia and its surrounding neighborhoods, Wistar colleagues united to run, walk and raise funds supporting our pre- and postdoctoral trainees. We had an amazing turn out, we all got our blood pumping on this brisk fall…
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Wistar Creates a New Synthetic DNA Vaccine Against Powassan Virus

PHILADELPHIA — (Oct. 29, 2020) — Scientists at The Wistar Institute have designed and tested the first-of-its-kind synthetic DNA vaccine against Powassan virus (POWV), targeting portions of the virus envelope protein. A rapidly reemerging tick-borne…
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National Institutes of Health Funding Powers Wistar Science in 2020

Approaching the end of the year, Wistar takes stock of its federal funding performance. During the 2020 fiscal year of the National Institutes of Health (NIH) — the U.S. government agency that supports biomedical research, it funded Wistar research…
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Advancement of Anticancer Compounds for B Cell Cancer Therapy Targeting a Cellular Stress Response Mechanism 

PHILADELPHIA — (Oct. 13, 2020) — Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the deve…
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