PHILADELPHIA — (Feb. 19, 2020) — Scientists at The Wistar Institute discovered a novel pathway that enables detection of DNA in the cytoplasm and triggers inflammation and cellular senescence. This…
PHILADELPHIA — (Jan. 30, 2020) — Combining EZH2 inhibition and PARP1 inhibition may provide a new therapeutic strategy for ovarian cancers that have functional DNA damage repair and thus would not …
PHILADELPHIA — (Jan. 24, 2020) — In a study by The Wistar Institute and collaborators, a rare, African-specific variant of the TP53 gene called P47S causes iron accumulation in macrophages and othe…
PHILADELPHIA — (Jan. 23, 2020) — The Wistar Institute announces today that they are part of a team to develop a vaccine against the recently emerged strain of coronavirus (2019-nCoV) that has infec…
PHILADELPHIA — (Jan. 11, 2020) — Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, …
PHILADELPHIA — (Dec. 19, 2019) — In the past six months, scientists at The Wistar Institute received funding from private foundations totaling $2,418,000 that will fuel new discoveries in cancer, i…
PHILADELPHIA — (Dec. 19, 2019) — A study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following …
PHILADELPHIA — (Dec. 17, 2019) — See cellular images as distinct as abstract art, minerals appear as future urban landscapes, single-celled organisms of the microscopic netherworld, and much more f…
PHILADELPHIA — (Nov. 14, 2019) — The Wistar Institute and Leiden University Medical Center (LUMC) formalized a memorandum of understanding between the two institutions to explore a postdoctoral tra…
PHILADELPHIA — (Nov. 8, 2019) — Scientists at The Wistar Institute applied synthetic DNA-based technology to drive in vivo production of broadly neutralizing anti-HIV antibodies in small and large-…
