The Wistar Institute

Today's Discoveries, Tomorrow's Cures.

Medical advances begin as scientific advances. The Wistar Institute is an independent nonprofit biomedical research institute dedicated to saving lives through science.
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Study Shows DNA-based Zika Vaccine is Safe and Effective

A vaccine developed by David Weiner and his colleagues was able to elicit an immune response in a phase I clinical trial.
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Genome Architecture Caught in Motion

Ken-ichi Noma and his lab have uncovered how the genetic material in the genome is compacted and de-compacted during the different phases of the cell cycle.
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Link Established Between Novel Class of Drugs and Melanoma Progression

Meenhard Herlyn and colleagues demonstrated how melanoma cells are able to rewire their signaling pathways to resist drug treatment.
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Newly Identified Pathway Controls Tumor Metabolic Reprogramming

The lab of Dario Altieri described how the pathway may be targeted to disrupt metastatic tumor cells.
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Wistar Shared Resources

Wistar's Shared Resources augment the power of individual labs with scientific expertise and technologies. They are available to all Wistar investigators, Wistar affiliates, and external researchers on a fee-for-service basis.

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Meet A Scientist

Qing Chen, M.D., Ph.D., focuses on brain metastasis, a significant clinical challenge due to its rising incidence and limited treatment options. She studies how cancer cells interact with surrounding brain cells to understand how a cancer can become metastatic.

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From The Wistar Wire

October 12, 2017

Wistar Science Highlights: Advances in Melanoma Biology, New Generation Immunotherapy for Antibiotic-resistant Bacterial Infection, New Aspects of the 3-D Organization of the Genome, and Wistar Scientist Selected for NIH Award

Wistar scientists have published new studies on fundamental aspects of melanoma metastasis and therapy resistance, the application of a novel immunotherapeutic technology to prevent infection with antibiotic-resistant bacteria, and the discovery of new aspects of the three-dimensional organization of the genome. Also, the National Institutes of Health (NIH) selected a Wistar principal investigator for her innovative epigenetics research. Read More >

October 9, 2017

Zika DNA Vaccine Proven Safe and Effective at Inducing Immunity

The vaccine, developed by David Weiner and his colleagues, has been proven safe and effective at generating an immune response in a clinical trial. Read More >

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Press Releases

October 9, 2017

Genome Architecture Caught in Motion

Study describes how the three-dimensional architecture of the genome changes during the cell cycle. Read More >

October 5, 2017

NIH Selects Wistar Scientist Kavitha Sarma, Ph.D., for New Innovator Award

National Institutes of Health “venture capital” grant awarded to early-career investigator for $1.5 million to pursue high-risk cancer research. Read More >

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