Wistar Wire: Genes

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Congratulations are in order for The Cancer Genome Atlas Network, for their publication in Nature over the weekend that announced the most comprehensive analysis of breast cancer genetics yet published. Their findings have shown how the disease can be categorized by four distinct genetic profiles, and have identified genetic markers within each category that might advance cancer care by providing new, druggable targets.
Cancer, Genes
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A BRAF inhibitor known as vemurafenib (Zelboraf) has been touted as a breakthrough melanoma treatment. But for some patients, the price of success is a mutation that leads to the development of secondary skin cancers called squamous cell carcinomas. In an editorial in The New England Journal of Medicine, Wistar researcher Ashani Weeraratna, Ph.D., discusses the success of a new combination treatment.
Cancer, Genes, Melanoma
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A news segment featuring Wistar Professor Louise C. Showe, Ph.D., aired on CBS3 on December 21, 2011 in the five o'clock broadcast. The segment discussed her work toward developing a blood test for lung cancer.
Cancer, Genes
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One reason why lung cancer is one of the deadliest forms of cancer in the United States is that it is so difficult to detect at its earliest stages, when treatment is most effective. But what if a simple blood test—no more invasive than having your cholesterol or blood sugar levels checked—could do the trick?
Cancer, Genes