Monoclonal Antibody for Delineating CD8+ T Cell Population Subsets (C1.7)

Inventor(s)

Giorgio Trinchieri and Nicholas Valiante

Tech ID
VN94134
Key Words
cytoxic T cells, Diagnostic, T cell, Therapeutic
Applications and Advantages

C1.7 binds to a unique surface marker expressed by a functionally distinct subset of CD8+ T cells. C1.7 can potentially provide a more accurate means of establishing and correlating CD8+ T cell subset predominance in certain diseases. The antibody could significantly advance studies to define the phenotypes, cytotoxic activity and cytokine profiles of CD8+ T cell subset populations.

Intellectual Property Status

This technology is protected by U.S. Patent No. 5,688,690.