Method of Producing a Stem Cell-Like Melanocyte
This technology is useful for developing dedifferentiated melanocyte for purposes of tissue reconstruction, tissue regeneration and repair as well as cancer stem cell research.
PCT Application No. PCT/US2009/058950 (WO 2010/038781, published 04/08/2010).
Wistar is seeking corporate partners to collaborate in further validation and development of technology.
Active Notch1 confers a transformed phenotype to primary human melanocytes., Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, Nickoloff BJ, Pear WS, Capobianco AJ, Herlyn M. Cancer Res. 2009 Jul 1;69(13):5312-20. Epub 2009 Jun 23.