Method of Producing a Stem Cell-Like Melanocyte
Inventor(s)
Tech ID
HM08001
Key Words
Cancer, cancer stem cells, dedifferentiation, melanocytes, oncology, tissue reconstruction., tissue regeneration, tissue repair
Applications and Advantages
This technology is useful for developing dedifferentiated melanocyte for purposes of tissue reconstruction, tissue regeneration and repair as well as cancer stem cell research.
Intellectual Property Status
PCT Application No. PCT/US2009/058950 (WO 2010/038781, published 04/08/2010).
Licensing Opportunity
Wistar is seeking corporate partners to collaborate in further validation and development of technology.
Relevant Publication(s)
Active Notch1 confers a transformed phenotype to primary human melanocytes., Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, Nickoloff BJ, Pear WS, Capobianco AJ, Herlyn M. Cancer Res. 2009 Jul 1;69(13):5312-20. Epub 2009 Jun 23.
