Introduction
The laboratory of Ramin Shiekhattar, Ph.D., is interested in the biochemical events that contribute to the development of cancer. The focus of the laboratory's research is the biochemical isolation of proteins encoded by genes known to be involved in human cancer. The Shiekhattar laboratory also studies the role of these proteins on normal cellular growth and uses cells derived from tumors to study the function of these genes in cell culture models.
How non-coding RNA-activators promote gene expression
These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some cancers, in adults.
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Funds Courtesy of PBCC & Pennsylvania Taxpayers
Ramin Shiekhattar, Ph.D., receives a $50,000 grant from the PA Breast Cancer Coalition to track down the molecular pathways that allow mutations in BRCA1, BRCA2, and PALB2 genes to drive breast and ovarian cancer.
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