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The laboratory of Ramin Shiekhattar, Ph.D., is interested in the biochemical events that contribute to the development of cancer. The focus of the laboratory's research is the biochemical isolation of proteins encoded by genes known to be involved in human cancer. The Shiekhattar laboratory also studies the role of these proteins on normal cellular growth and uses cells derived from tumors to study the function of these genes in cell culture models.
These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some cancers, in adults.Read more>
Ramin Shiekhattar, Ph.D., receives a $50,000 grant from the PA Breast Cancer Coalition to track down the molecular pathways that allow mutations in BRCA1, BRCA2, and PALB2 genes to drive breast and ovarian cancer.Read more>
The microscope in the image belonged to William E. Horner, M.D., a collaborator with Caspar Wistar, M.D., in the early 1800s.
Dr. Horner, a lecturer at the University of Pennsylvania, was a pioneer of the use of microscopes in anatomical and medical research. He authored Special Anatomy and Histology, a seminal text on the subject.