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The Wistar Institute

3601 Spruce Street

Philadelphia, PA 19104

 

Office: 215-495-6820

 

Selected Publications

1 - Hu, H. and Moller, G. (1993) Lipopolysaccharide-stimulated events in B cell activation. Scand. J. Immunol. 40, 221-227.

2 - Hu, H., Abedi-Valugerdi, M. and Moller, G. (1997) Pretreatment of lymphocytes with mercury in vitro induces a response in T cells from genetically determined low-responders and a shift of the interleukin profile. Immunology. 90, 198-204.

3 - Hu, H., Moller, G. and Abedi-Valugerdi, M. (1997) Thiol compounds inhibit mercury-induced immunological and immunopathological alterations in susceptible mice. Clin. Exp. Immunol. 107, 68-75.

4 - Hu, H., Moller, G. and Abedi-Valugerdi, M. (1997) Major histocompatibility complex Class II antigens are required for both cytokine production and proliferation induced by mercuric chloride in vitro. J. Autoimmun. 10, 441-446.

5 - Abedi-Valugerdi, M., Hu, H. and Moller, G. (1997) Mercury-induced renal immune complex deposits in young (NZBxNZW)F1 mice: Characterization of antibodies/autoantibodies. Clin. Exp. Immunol. 110, 86-91.

6 - Hu, H., Abedi-Valugerdi, M. and Moller, G. (1998) Non-responsiveness of mercury-induced autoimmunity in resistant mice is not due to immunosuppression or biased Th1-type response. Scand. J. Immunol. 48, 515-521.

7 - Abedi-Valugerdi, M., Hu, H. and Moller, G. (1999) Mercury-induced anti-nucleolar autoantibodies can transgress the membrane of living cells in vivo and in vitro. Int. Immunol. 11(5), 605-615.

8 - Hu, H., Moller, G. and Abedi-Valugerdi, M. (1999) Mechanism of mercury-induced autoimmunity: both T helper 1- and T helper 2-type responses are involved. Immunology. 96, 348-357.

9 - Swain, S. L., Hu, H. and Huston, G.  (1999) Class II independent generation of CD4 memory T cells from effectors.  Science. 286, 1381-1383.

10 - Whitehurst, C. E., Hu, H., Ryu, C. J., Rajendran, P., Schmidt, T. and Chen, J. (2001) V(D)J recombination and expression of TCR b occurs normally in the absence of the Jb2-Cb2 intronic Cis element. Mol. Immunol. 38, 55-63.

11 - Hu, H., Huston, G., Duso, D., Lepak, N., Roman, E. and Swain, S.L. (2001) CD4 T cell effectors can become memory cells with high efficiency and without division. Nature Immunology. 2, 705-710.

12 - Ge, Q., Hu, H., Eisen, H.N. and Chen, J (2002) Naïve to memory T-cell differentiation during homeostasis-driven proliferation. Microbes & Infection. 4, 555-558.

13 - Ge, Q., Hu, H., Eisen, H.N. and Chen, J (2002) Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naïve and memory T cell compartments. Proc.Natl. Acad. Sci. USA 99, 2989-2994.

14 - Hu, H., Wang, B., Borde, M., Maika, S., Nardone, J., Allred, L., Tucker, P.W. and Rao, A (2006) Foxp1 is an essential transcriptional regulator of B cell development. Nature Immunology. 7, 819-826 (see News and Views in Nat. Immunol. 7, 793-794).

15 - Hu, H., Djuretic, I., Sundrud, M.S. and Rao, A. (2007) Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT. Trends. Immunol. 28, 329-332.

16 - Bai, A., Hu, H., Yeung, M. and Chen, J. (2007) Kruppel-like factor 2 controls T cell trafficking by activating L-selection (CD62L) and sphingosine-1-phosphate receptor 1 transcription. J. Immunol. 178, 7632-7639.

17 - Feng, X., Ippolito, G. C., Tian, L., Karla, W., Oh, S., Sambandam, A., Willen, J., Bunte, R. M., Maika, S. D., Harriss, J.V., Caton, A. J., Bhandoola, A., Tucker, P. W., and Hu, H. (2010) Foxp1 is an essential transcriptional regulator for the generation of quiescent naïve T cells during thymocyte development. Blood. 115, 510-518.

18 - Feng, X., Wang, H., Takada, H., Day, T., Willen, J. and Hu, H. (2011) Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells. Nature Immunology. 12, 544-550 (see News and Views in Nat. Immunol. 12, 522-524; also featured as Article of the month).