Monday, May 20, 2013 marks The Wistar Institute’s 18th annual Albert R. Taxin Golf & Bridge Classic at Green Valley Country Club.

The Wistar Institute Melanoma Awareness Day

with the Philadelphia Phillies!

Presented by Citizens Bank and Independence Blue Cross

Sunday, May 19^th at 1:30 p.m. vs. the Cincinnati Reds
Tickets: $28, (Pavilion Deck Section 307 and 308)
**A portion of each ticket purchase benefits
The Wistar Institute Melanoma Research Center    

Purchase Tickets at www.phillies.com/wistar.

Learn more about Melanoma Awareness Day at Citizen's Bank Park.

Support melanoma research at Wistar. 

Robert A. Weinberg, Ph.D., of Whitehead Institute for Biomedical Research will present this lecture at 10:00 a.m. in the Grossman Auditorium. 

Free and open to the public. For more information, call 215-898-3944.

Carcinoma cells undergo a profound phenotypic shift within primary tumors termed the epithelial-mesenchymal transition (EMT), which imparts to them many of the attributes of mesenchymal cells, including motility, invasiveness and a heightened resistance to apoptosis.  This empowers cancer cells to disseminate from primary tumors and, at the same time, to serve as founders of distant metastatic colonies.  This program appears to be triggered by contextual signals that carcinoma cells receive from the nearby stromal microenvironment that is generated as primary tumors develop. The phenotypic changes that the EMT program  confers may be reversed when disseminated carcinoma cells encounter a novel microenvironment in a distant tissues, explaining the histopathologic resemblance between primary tumors and their derived metastases.

Carlo Croce, M.D., of the Ohio State University will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

M. Celeste Simon, Ph.D., of the University of Pennsylvania will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Join us for this Philadelphia Science Festival event!

Logan Circle will be transformed into a science wonderland! Free all day.

This event is part of the Philadelphia Science Festival, taking place April 18 to 28, 2013. Check out the other amazing events as well!

Kornelia Polyak, M.D., Ph.D., of Harvard University will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Professor Giulio Cossu of University College London will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Douglas Wallace, Ph.D., of the Children’s Hospital of Philadelphia will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Murray Korc, M.D., of the Indiana University School of Medicine will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Tak Mak, Ph.D., of the University of Ontario will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

An exhibition of award-winning photography through the microscope.

In the image: 2012 Image of Distinction: James E. Hayden, The Wistar Institute Imaging Facility
Down and belly feather from a Yellow-bellied Sapsucker (200x magnification)

Steven A. Rosenberg, M.D., Ph.D. of the NCI will present this lecture.

Free and open to the public. For more information, call 215-898-3944.

Scott Lowe, Ph.D., from Memorial-Sloan Kettering Cancer Center will present this lecture.

The Wistar Institute Celebrates 40 Years as an NCI-Designated Cancer Center

John Quackenbush, Ph.D., from the Dana-Farber Cancer Institute will present this lecture.

Roel Nusse, Ph.D., from Stanford University will present this lecture.

Louis M. Staudt, M.D., Ph.D., from NIH will present this lecture.

David Rose, Archivist of the March of Dimes, will explore the impact of polio and rubella in American life and the vaccines that led to their decline.

Stephen Baylin, M.D., from Johns Hopkins University will present this lecture.

Frank McCormick, Ph.D., FRS, from the University of California, San Francisco will present this lecture.

Sam Kean discusses his book The Violinist's Thumb followed by an interview with Marty Moss-Coane, host of WHYY's Radio Times.

Join us for a fun and fulfilling morning at the Wells Fargo Center on Sunday, June 24, 2012, for the Annual Noreen O’Neill Foundation for Melanoma Research Running for Cover Run/Walk. The money raised benefits the Melanoma Research Center at The Wistar Institute.

Events this year include:

* 5K Run
* 1 Mile Walk
* ½ Mile Junior Dash (ages 10 and under)

Whether you walk, run, or just want to come out and cheer us on, it’s a fun day for all! Children and dogs are welcome.

John Rinn, Ph.D. of Harvard University will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Thank you to all our sponsors, volunteers, and participants!

Save the date for the 18th Annual Albert R. Taxin Golf & Bridge Classic: Monday, May 20, 2013.

Richard G. Pestell, M.D., Ph.D. will present this lecture.
This event is free and open to the public. For more information, call 215-898-3944.

Eric Fearon, Ph.D. of the University of Michigan will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Robert Neil Eisenman, Ph.D. of the Fred Hutchinson Cancer Research Center will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Uncover Philadephia's scientific history!

This event is part of the Philadelphia Science Festival, taking place April 20 to 29, 2012. Check out the other amazing events as well!

Discover how the visual journey of medical illustration reflects our cultural history and see the evolution from classical illustration to today’s medical illustration, which includes the animation of dynamic molecular and cellular processes, simulation, virtual and augmented reality, gaming, and mobile media.

This event is part of the Philadelphia Science Festival, taking place April 20 to 29, 2012. Check out the other amazing events as well!

This event brings together noted vaccine experts to discuss the recent debate surrounding vaccination.

This event is part of the Philadelphia Science Festival, taking place April 20 to 29, 2012. Check out the other amazing events as well!

Logan Circle will be transformed into a science wonderland! Free all day.

This event is part of the Philadelphia Science Festival, taking place April 20 to 29, 2012. Check out the other amazing events as well!

Every April, Philadelphia's schools, universities, cultural institutions, and research centers unite as one to put science in the spotlight. Scientists and engineers throughout the city offer fun, interactive programs for Philadelphians of all ages. 

The Philadelphia Science Festival will take place from April 20 to 29, 2012.

Perry Nisen, M.D., Ph.D. of GlaxoSmithKline will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Jean-Pierre Issa, M.D., of Temple University will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

THE PRESIDENT’S AWARD recognizes a public figure who not only has confronted cancer, but also has served as an advocate for improvements in cancer education and research. The award also acknowledges the Institute’s most generous supporters.

Attendance at this event is by invitation only.  For more information, call 215-898-3955.

Eric Olson, Ph.D., of the University of Texas, will present this lecture.

This event is free and open to the public. Due to limited space, registration is required. To register, please email Maria Colelli.

Chi Van Dang, M.D., Ph.D., Director of the Abramson Cancer Center of the University of Pennsylvania, will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Kenneth W. Kinzler, Ph.D. of Johns Hopkins University will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

Gregory J. Hannon, Ph.D. of Cold Spring Harbor Laboratory will present this lecture.

This event is free and open to the public. For more information, call 215-898-3944.

The Wistar Institute Leadership Council invites you to the opening reception of the Nikon Small World exhibition.

Discover the beauty and complexity of life as seen through today’s advanced microscopes.

Joan S. Brugge, Ph.D. of Harvard University will present this lecture.

Tumorigenesis is a clonal evolution process initiated from single cells within otherwise histologically normal tissue. How single, sporadic mutant cells that have sustained oncogenic alterations evolve within tightly regulated tissue environment remains elusive.

Dr. Brugge's laboratory has investigated the effects of inducing oncogene expression in single cells within organotypic mammary acini as a model to elucidate the processes by which oncogenic alterations initiate clonal progression from organized epithelial environments. The studies that she will present  show that initiation of outgrowth of a single oncogene-expressing cell from organized epithelial structures is a highly regulated process, and involving a cell translocation mechanism that allows sporadic mutant cells to evade suppressive microenvironments and provokes clonal selection for survival and proliferative expansion outside their native niches.

This event is free and open to the public. For more information, call 215-898-3944.

Vincent J. Cristofalo Memorial Lecture
Cancer and Aging: Rival Demons?
Judith Campisi, Ph.D.
Professor, Buck Institute for Research on Aging

Myeloid-derived Suppressor Cells as a Critical Element of Tumor Microenvironment:
Biological Role and Target for Therapeutic Intervention
Dmitry Gabrilovich, M.D., Ph.D.
H. Lee Moffitt Cancer Center & Research Institute

Computational Approaches for Predicting Transcription Factor Interactions

Mona Singh, Ph.D.
Princeton University

The Wistar Institute’s Authors Series

Rob Dunn, Ph.D., discusses his book The Wild Life of Our Bodies: Predators, Parasites, and Partners That Shape Who We Are Today.

New Ways of Thinking About Multidrug Resistance in Cancer

George Khoury Memorial Lecture

Michael Gottesman, M.D.
Chief, Laboratory of Cell Biology, CCR, NCI, NIH

Presented at the Wistar Gala, the Wistar Award is a biennial award given to an individual who reflects the qualities of compassion, integrity, generosity, commitment, and vision that the Institute’s founding members demonstrated.

This year's gala honored Adele K. Schaeffer.

The Biology and Therapeutics of RAS and BRAF Signalling in Melanoma

Richard Marais, Ph.D., FMed Sci
Professor of Molecular Oncology
The Institute of Cancer Research

The Wistar Institute and Nicole Miller invite you to a special
Girls Night Shopping Event.

Genetic Analysis of Melanocyte Development and Its Implications for Melanoma

William Pavin, Ph.D.
Senior Investigator, NHGRI, NIH

Targeting JAK-STAT Signaling for Cancer Therapy

Richard Jove, Ph.D.
Director, Beckman Research Institute
City of Hope Cancer Center

The Wistar Institute is pleased to present this public symposium.

Jefferson Medical College Department of Cancer Biology professor Lucia Languino, Ph.D., will give a presentation on the latest prostate cancer research, focusing on progress towards new treatments for the disease, and emerging trends in prostate cancer care.

This event is free, but registration is required. Limited to first 100 registrants. Register by calling 215-898-3930.

Made possible in partnership with the American Cancer Society, PA Division, Inc. and Community Leadership Council for the Abramson Cancer Center.

In 1993, Philadelphia lost one its most beloved citizens, Albert Taxin, from an inoperable brain tumor. Albert was 53 years of age. He was well known by many throughout Philadelphia and by visitors to our city as the owner and operator of the famous Old Original Bookbinders restaurant.

In 1999 to memorialize Albert and to raise awareness of, and funds for, brain tumor research, Albert's widow, Doris Taxin, established the Albert R. Taxin Brain Tumor Research Center at The Wistar Institute. 

The sole purpose of this event is to raise funds for more research and empower scientific advances into therapies for those who are afflicted with brain tumors and neurological diseases. Through the commitment and dedication of all who support this event, progress is being made.