18th Annual Albert R. Taxin Golf & Bridge Classic - May 20, 2013
Monday, May 20, 2013 marks The Wistar Institute’s 18th annual Albert R. Taxin Golf & Bridge Classic at Green Valley Country Club.Read More >
Melanoma Awareness Day at Citizens Bank Park - May 19, 2013
The Wistar Institute Melanoma Awareness Day
with the Philadelphia Phillies!
Presented by Citizens Bank and Independence Blue Cross
Sunday, May 19th at 1:30 p.m. vs. the Cincinnati Reds
Tickets: $28, (Pavilion Deck Section 307 and 308)
**A portion of each ticket purchase benefits
The Wistar Institute Melanoma Research Center
Purchase Tickets at www.phillies.com/wistar.
Learn more about Melanoma Awareness Day at Citizen's Bank Park.
Support melanoma research at Wistar.
Mechanisms of Metastatic Dissemination - May 15, 2013
Robert A. Weinberg, Ph.D., of Whitehead Institute for Biomedical Research will present this lecture at 10:00 a.m. in the Grossman Auditorium.
Free and open to the public. For more information, call 215-898-3944.Mechanisms of Metastatic Dissemination
Carcinoma cells undergo a profound phenotypic shift within primary tumors termed the epithelial-mesenchymal transition (EMT), which imparts to them many of the attributes of mesenchymal cells, including motility, invasiveness and a heightened resistance to apoptosis. This empowers cancer cells to disseminate from primary tumors and, at the same time, to serve as founders of distant metastatic colonies. This program appears to be triggered by contextual signals that carcinoma cells receive from the nearby stromal microenvironment that is generated as primary tumors develop. The phenotypic changes that the EMT program confers may be reversed when disseminated carcinoma cells encounter a novel microenvironment in a distant tissues, explaining the histopathologic resemblance between primary tumors and their derived metastases.
- Causes and Consequences of microRNA Dysregulation in Cancer - May 8, 2013
- Hypoxia, HIFs and Tumor Progression - April 24, 2013
- How Medicine Works: A Microscopic Army - April 23, 2013
- Philadelphia Science Carnival - April 20, 2013
- Heterogeneity in Breast Cancer - April 4, 2013
- 3rd Annual Clayton Buck Lecture: Cell Therapies for Muscular Dystrophies - March 27, 2013
- Mitochondrial bioenergetics and the etiology of metabolic and degenerative disease aging and cancer - March 13, 2013
- Rb or not Rb: Final Common Pathway in PDAC? - February 27, 2013
- Cancer Metabolism: Back to the Future (Trainee Sponsored Lecture) - February 13, 2013
Nikon Small World Exhibition - February 1, 2013
An exhibition of award-winning photography through the microscope.
In the image: 2012 Image of Distinction: James E. Hayden, The Wistar Institute Imaging FacilityRead More >
Down and belly feather from a Yellow-bellied Sapsucker (200x magnification)
- Autologous T Cells as a Personalized Treatment for Patients with Cancer - January 30, 2013
Identifying Tumor Suppressor and Tumor Maintenance Genes Using Mouse Models and RNA Interference - December 5, 2012
Scott Lowe, Ph.D., from Memorial-Sloan Kettering Cancer Center will present this lecture.Read More >
- From 1972 to 2012 and Beyond - November 15, 2012
Moving Beyond the Mean: The Role of Variation in Determining Phenotype - November 7, 2012
John Quackenbush, Ph.D., from the Dana-Farber Cancer Institute will present this lecture.Read More >
- Wnt signaling, stem cells, and tissue maintenance - October 24, 2012
- Therapeutic Strategies in Lymphoma Inspired by Functional and Structural Genomics - October 10, 2012
Vaccines and the March of Dimes: From Polio to Rubella - October 1, 2012
David Rose, Archivist of the March of Dimes, will explore the impact of polio and rubella in American life and the vaccines that led to their decline.Read More >
- The DNA Methylation Component of the Cancer Epigenome – Biological and Translational Implications - September 19, 2012
The RAS Pathway in Cancer - September 13, 2012
Frank McCormick, Ph.D., FRS, from the University of California, San Francisco will present this lecture.Read More >
Authors Series: Sam Kean, author of The Violinist's Thumb - September 11, 2012
Sam Kean discusses his book The Violinist's Thumb followed by an interview with Marty Moss-Coane, host of WHYY's Radio Times.Read More >
Running for Cover Run/Walk - June 24, 2012
Join us for a fun and fulfilling morning at the Wells Fargo Center on Sunday, June 24, 2012, for the Annual Noreen O’Neill Foundation for Melanoma Research Running for Cover Run/Walk. The money raised benefits the Melanoma Research Center at The Wistar Institute.
Events this year include:
* 5K Run
* 1 Mile Walk
* ½ Mile Junior Dash (ages 10 and under)
Whether you walk, run, or just want to come out and cheer us on, it’s a fun day for all! Children and dogs are welcome.
- Linking RNA to human health - May 30, 2012
17th Annual Albert R. Taxin Golf & Bridge Classic - May 21, 2012
Thank you to all our sponsors, volunteers, and participants!
Save the date for the 18th Annual Albert R. Taxin Golf & Bridge Classic: Monday, May 20, 2013.Read More >
- Non-canonical functions of cyclins - May 21, 2012
- Modeling the molecular pathogenesis of colorectal cancer - May 9, 2012
- Waking a Sleeping Dragon: Activation of the Myc Oncoprotein - May 2, 2012
- Science Scavenger Hunt - April 28, 2012
Visualizing the Body Beautiful - April 27, 2012
Discover how the visual journey of medical illustration reflects our cultural history and see the evolution from classical illustration to today’s medical illustration, which includes the animation of dynamic molecular and cellular processes, simulation, virtual and augmented reality, gaming, and mobile media.
This event is part of the Philadelphia Science Festival, taking place April 20 to 29, 2012. Check out the other amazing events as well!Read More >
- The Great Vaccine Debate - April 24, 2012
- Philadelphia Science Carnival - April 21, 2012
Philadelphia Science Festival - April 20, 2012
Every April, Philadelphia's schools, universities, cultural institutions, and research centers unite as one to put science in the spotlight. Scientists and engineers throughout the city offer fun, interactive programs for Philadelphians of all ages.
The Philadelphia Science Festival will take place from April 20 to 29, 2012.Read More >
Breakthrough science and the next wave of cancer therapeutics - April 18, 2012
Perry Nisen, M.D., Ph.D. of GlaxoSmithKline will present this lecture.
This event is free and open to the public. For more information, call 215-898-3944.Read More >
- Death, taxes, and DNA methylation drift - April 11, 2012
The President's Award - March 21, 2012
THE PRESIDENT’S AWARD recognizes a public figure who not only has confronted cancer, but also has served as an advocate for improvements in cancer education and research. The award also acknowledges the Institute’s most generous supporters.
Attendance at this event is by invitation only. For more information, call 215-898-3955.Read More >
- Heart making and heart breaking: The molecular circuitry of cardiac development, disease and regeneration - March 14, 2012
- Targeting MYC-regulated cancer cell metabolism - March 7, 2012
- Lessons from the cancer genome - February 15, 2012
- Conserved roles of small RNAs in genome defense - February 8, 2012
Nikon Small World Exhibition Opening Reception - February 3, 2012
The Wistar Institute Leadership Council invites you to the opening reception of the Nikon Small World exhibition.
Discover the beauty and complexity of life as seen through today’s advanced microscopes.Read More >
Mechanisms that regulate clonal expansion of oncogene-expressing cells in normal tissue environments - January 11, 2012
Joan S. Brugge, Ph.D. of Harvard University will present this lecture.
Tumorigenesis is a clonal evolution process initiated from single cells within otherwise histologically normal tissue. How single, sporadic mutant cells that have sustained oncogenic alterations evolve within tightly regulated tissue environment remains elusive.
Dr. Brugge's laboratory has investigated the effects of inducing oncogene expression in single cells within organotypic mammary acini as a model to elucidate the processes by which oncogenic alterations initiate clonal progression from organized epithelial environments. The studies that she will present show that initiation of outgrowth of a single oncogene-expressing cell from organized epithelial structures is a highly regulated process, and involving a cell translocation mechanism that allows sporadic mutant cells to evade suppressive microenvironments and provokes clonal selection for survival and proliferative expansion outside their native niches.
This event is free and open to the public. For more information, call 215-898-3944.Read More >
Cancer and Aging: Rival Demons? - December 7, 2011
Vincent J. Cristofalo Memorial LectureRead More >
Cancer and Aging: Rival Demons?
Judith Campisi, Ph.D.
Professor, Buck Institute for Research on Aging
Myeloid-derived Suppressor Cells as a Critical Element of Tumor Microenvironment - November 16, 2011
Myeloid-derived Suppressor Cells as a Critical Element of Tumor Microenvironment:Read More >
Biological Role and Target for Therapeutic Intervention
Dmitry Gabrilovich, M.D., Ph.D.
H. Lee Moffitt Cancer Center & Research Institute
Computational Approaches for Predicting Transcription Factor Interactions - November 9, 2011
Computational Approaches for Predicting Transcription Factor Interactions
Mona Singh, Ph.D.Read More >
Authors Series: Rob Dunn, author of The Wild Life of Our Bodies - November 8, 2011
The Wistar Institute’s Authors Series
Rob Dunn, Ph.D., discusses his book The Wild Life of Our Bodies: Predators, Parasites, and Partners That Shape Who We Are Today.Read More >
New Ways of Thinking About Multidrug Resistance in Cancer - November 3, 2011
New Ways of Thinking About Multidrug Resistance in Cancer
George Khoury Memorial Lecture
Michael Gottesman, M.D.
Chief, Laboratory of Cell Biology, CCR, NCI, NIH
The Wistar Gala - October 29, 2011
Presented at the Wistar Gala, the Wistar Award is a biennial award given to an individual who reflects the qualities of compassion, integrity, generosity, commitment, and vision that the Institute’s founding members demonstrated.
This year's gala honored Adele K. Schaeffer.Read More >
The Biology and Therapeutics of RAS and BRAF Signalling in Melanoma - October 20, 2011
The Biology and Therapeutics of RAS and BRAF Signalling in Melanoma
Richard Marais, Ph.D., FMed SciRead More >
Professor of Molecular Oncology
The Institute of Cancer Research
Nicole Miller Shopping Event - October 6, 2011
The Wistar Institute and Nicole Miller invite you to a specialRead More >
Girls Night Shopping Event.
- History Live: “Cancer Therapies: 19th Century to Tomorrow” - October 5, 2011
Genetic Analysis of Melanocyte Development and Its Implications for Melanoma - October 5, 2011
Genetic Analysis of Melanocyte Development and Its Implications for Melanoma
William Pavin, Ph.D.Read More >
Senior Investigator, NHGRI, NIH
Targeting JAK-STAT Signaling for Cancer Therapy - September 21, 2011
Targeting JAK-STAT Signaling for Cancer Therapy
Richard Jove, Ph.D.Read More >
Director, Beckman Research Institute
City of Hope Cancer Center
Advances in Prostate Cancer Research - September 15, 2011
The Wistar Institute is pleased to present this public symposium.
Jefferson Medical College Department of Cancer Biology professor Lucia Languino, Ph.D., will give a presentation on the latest prostate cancer research, focusing on progress towards new treatments for the disease, and emerging trends in prostate cancer care.
This event is free, but registration is required. Limited to first 100 registrants. Register by calling 215-898-3930.
Made possible in partnership with the American Cancer Society, PA Division, Inc. and Community Leadership Council for the Abramson Cancer Center.Read More >
16th Annual Albert R. Taxin Golf & Bridge Classic - May 22, 2011
In 1993, Philadelphia lost one its most beloved citizens, Albert Taxin, from an inoperable brain tumor. Albert was 53 years of age. He was well known by many throughout Philadelphia and by visitors to our city as the owner and operator of the famous Old Original Bookbinders restaurant.
In 1999 to memorialize Albert and to raise awareness of, and funds for, brain tumor research, Albert's widow, Doris Taxin, established the Albert R. Taxin Brain Tumor Research Center at The Wistar Institute.
The sole purpose of this event is to raise funds for more research and empower scientific advances into therapies for those who are afflicted with brain tumors and neurological diseases. Through the commitment and dedication of all who support this event, progress is being made.Read More >