Cancer and Aging: Rival Demons?

Cancer and Aging: Rival Demons?

Cancer and Aging: Rival Demons?

Wednesday, December 7, 2011 - 4:00pm

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA

Vincent J. Cristofalo Memorial Lecture
Cancer and Aging: Rival Demons?
Judith Campisi, Ph.D.
Professor, Buck Institute for Research on Aging

Age is the largest single risk factor for the development of cancer.  Recent findings suggest that the relationship between age and the incidence of cancer—and, indeed, the incidence of many age-related diseases—is not simply a matter of time.  Rather, some of the powerful mechanisms that evolved to keep cancer at bay may, at advanced ages, fuel age-related pathology.  I will discuss the complexities of cellular senescence and how it may hold the key to achieving an optimal balance between tumor suppression, tissue repair, cancer progression, and aging.